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Affect is a verb, meaning to cause something to happen. Effect is a noun, which is the result of having happened. Here are two sentences that illustrate:
Mary wondered if her tutoring of John would beneficially affect his grades. ( "Affect" to cause his grades to improve --Verb)
John got an A on his exam, due to the positive effect of Mary's tutoring. ("Effect" the positive result of Mary's tutoring -- Noun)
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