2 Answers

Check your device manager to see if the drives show up at all. If they show up as disabled or with warnings, uninstall them and then go to "Action" then "Scan for Hardware Changes". This will make Windows rescan your devices and re-install the cd-rom drivers.

If it still shows up as being unable to start, there is a registry fix available on Microsoft's website.

http://support.microsoft.com/kb/314060

If the drivers are installed properly and the drive isn't listed with problems, you may just need to assign it a drive letter.
Right click on "My Computer" and then on "Manage". There you will find the "Disk Management" console where you can assign it a drive letter.

If your computer doesn't recognize the CD, the problem might be that the CD is damaged or empty, or that your CD reader is broken. You can try running other CDs, and if they run, then the CD with the drivers has a problem, and if the other CDs won’t run, the problem seems to be with the reader, in which case you should have a computer technician help in replacing or fixing it.