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According to the American Kennel Club, the largest breed of dog is the English Mastiff, also known as the Old English Mastiff. Mastiffs are considered the heaviest dog breed, but not necessarily the tallest. They can weigh anywhere from 110 lbs to 343 lbs. The height of a mastiff can range from 25 inches at the shoulder to 36 inches.
http://thehydrant.wordpress.com/2011/07/13/worldslargestbreeds/
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