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By Mayo Clinic staff
Kidney stones often have no definite, single cause. A number of factors, often in combination, create the conditions in which susceptible people develop kidney stones.
Kidney stones form when the components of urine — fluid and various minerals and acids — are out of balance. When this happens, your urine contains more crystal-forming substances, such as calcium, oxalate and uric acid, than the available fluid can dilute. At the same time, your urine may be short of substances that keep crystals from sticking together and becoming stones. This creates an environment in which kidney stones are more likely to form.