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FROM >>> http://www.netdoctor.co.uk/travel-health/medicines/quinine-sulphate.html
Quinine is also sometimes used to treat recurrent night-time leg cramps, for instance in people with arthritis, diabetes or varicose veins. It is thought to prevent muscle cramps by reducing the sensitivity of muscle cells to stimuli that cause them to contract, as well as by prolonging the time it takes for the muscle to contract. It can take up to four weeks of taking quinine before an improvement in leg cramps is seen. If it hasn't helped after four weeks then it should be stopped.
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