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Acetaminophen/hydrocodone is used in the treatment of back pain; pain; rheumatoid arthritis; cough and belongs to the drug class narcotic analgesic combinations. Risk cannot be ruled out during pregnancy. Acetaminophen/hydrocodone 500 mg / 5 mg is classified as a Schedule 2 controlled substance under the Controlled Substance Act (CSA).

The link next version of the 5516 above left offers an entirely different layout with the moon-phase at twelve and the date aligned to the periphery with a centrally mounted date hand. This second take of the brand's perpetual calendar wristwatch also lacked a leap-year display and made use of a more ornate case and lug design. Two link such examples are known to have been produced with the first delivered to Gubelin in 1950 and the second sold to Patek Philippe link in New York sometime during 1962.