after many years of being on everything under the sun i have found this combination working great for my depression and anxiety i now take topomax , pristique, zanax for anxiety and ambien for sleep i too started out on lithium had all the side effects and being a hair dresser i had to stop taking it my hands shook so bad by the way the side effects of most all mental health meds. is weight gain but to my surprise the side effects, of Topomax is loss of appitite and weight loss, i couldnt tell a difference in the first couple of months then i began to notice my pants getting loose so this gave me the courage to go one step further and now ive started eating better and walking and u know what i am now down from a size 20 to a size 16 ask your Dr. to at least let you try it for a while you have nothing to lose but weight!!!!strong text