A good example is the definition of a gentleman. One who knows how to play the bagpipes, but doesn't.

He is both knowledgeable, and wise.

A broader question is "What are the pros and cons of recreational drugs?" The answer could fill a PhD thesis. However, very briefly AGAINST:- Most are illegal, and most have harmful side effects. The probability of a given side effect coming from a particular drug might be very low, or very high, or not yet known. FOR:- (a) Personal liberty. Assuming you are fully informed, you should be allowed to do just about anything with your body. (b) Some, in fact most, give pleasure in some form. Life is to be enjoyed, even if the enjoying shortens it.